Likutei Moharan, Part II 3:2/ליקוטי מוהר"ן·תנינא ג׳:ב׳

12. This is also [hinted at by] the difference in the punctuation between rapo and yerapei. Whereas rapo is [vowelized] with a cholam, yerapei is with a tzeirei. The cholam signifies mitigation. This is as is brought in the writings of the Ari, of blessed memory: ChoLaM has the same numerical value as three times YHVH, which mitigate the three Elohim in the throat. These [three] are the constricted mentalities that descend to the throat, and are mitigated by the three YHVH, the numerical value ChoLaM.

2Then, after the mitigation, it is yerapei, with a TZeiReI, as in “Is there no TZaRI (balm) in Gilead? Is there no healer there?” (Jeremiah 8:22). This alludes to healing. Only after the mitigation, which is rapo with a cholam, can one cure using medicines, which is yerapei, with a tzeirei.