Or HaChaim on Genesis 28:10/אור החיים על בראשית כ״ח:י׳

1 ויצא יעקב. Jacob departed. The reason that the Torah did not content itself with reporting Jacob's setting out for Padan Aram (28,5) and repeats his departure at this point is to allude to the encounters he had on the way. This, of course, raises the question why the Torah had first reported Jacob as already on the way to Padan Aram. This is especially curious in view of the encounter Jacob had on the way occurring before he even came close to Charan. Why did the Torah report events in a chronologically inverted manner? Besides, why did the Torah speak about חרנה instead of about Jacob being on the way לחרן? While it is true as we learn from Bereshit Rabbah 68,8 that any word which requires a letter ל as a prefix may instead have the letter ה as a suffix, the Torah surely does not employ these variations arbitrarily!

2The Torah intended to relate all that happened to Jacob from the time he left his home. The Torah reports that initially all Jacob did was depart, i.e. ויצא. This did not involve any travelling on his part. The person who walked i.e. וילך, was someone called חרנה. This "Charanah" set out from his home to come and welcome Jacob.

3It also possible that the Torah meant to convey to us that Esau's anger חרונו, departed from him the moment Jacob departed from Beer Sheva. This is expressed by the words: וילך חרנה.

4According to the tradition quoted by our sages that Esau sent his son Eliphaz after Jacob, the words וילך חרנה may allude to Eliphaz hurrying after Jacob full of anger, i.e. בחרון. Perhaps the next verse in which Jacob is described as encountering a certain site, ויפגע במקום, is a hint that Jacob felt endangered and took refuge in prayer.