Sforno on Genesis 28:20/ספורנו על בראשית כ״ח:כ׳

1אם יהיה אלוקים עמדי, to remove from me all the pressures which I am under, pressures which prevent man from giving his attention to matters which should receive his attention, i.e. to G’d and what He expects from man. What troubled Yaakov was what our sages in Eyruvin 41 described as the three problems which are liable to unbalance someone’s mind as well as his relationship to his Creator. They are: gentiles, being involved personally in natural disasters, and excessive poverty.

2ושמרני, from wicked gentiles who would force him to change his lifestyle;

3ונתן לי לחם לאכול, so that I will not be forced to violate both my own integrity and that ordained for me by my Maker.