Sforno on Genesis 44:22/ספורנו על בראשית מ״ד:כ״ב

1לא יוכל הנער לעזוב את אביו, from the moment he will have left his father, he will pine for his father and become sick or die. Furthermore,

2ועזב את אביו ומת, also his father will die without question if the lad leaves him.