Sforno on Leviticus 18:29/ספורנו על ויקרא י״ח:כ״ט

1כי כל אשר יעשה מכל התועבות האלה ונכרתו הנפשות, the reason why the land will spit you out if you violate even only part of these laws is that each one is a sufficiently serious violation in My eyes causing the deliberate perpetrator to be punished with the penalty of karet, total separation from the future of the people of the Jewish nation.